450 Patients in 30 Days: How a Leading Pharma Company Scaled Cardiovascular Trial Enrollment with Curebase

Curebase eClinical Platform · Clinical Trial Technology Case Study

Cardiovascular trials are among the hardest to recruit for because the patient population is broad and traditional recruitment methods move slowly. For one global pharmaceutical company, the answer was not more sites or bigger budgets: it was a smarter eClinical platform.

The Challenge

Recruiting patients for a cardiovascular study means competing for a population that is often older, less digitally engaged, and already managing complex health situations. Sponsors cannot rely on patients finding them. They need to go where patients already are, earn their trust quickly, and make participation feel accessible. The sponsor needed a recruitment model that could operate at scale without adding clinical site overhead. Curebase provided the clinical trial technology layer to make it possible.

The Approach

Rather than routing recruitment through traditional site networks, the sponsor partnered with a national pharmacy chain to tap into an existing, trusted relationship with the target patient population. The pharmacy identified patients in their network who matched the study's eligibility profile and passed that list through to the campaign workflow. From there, Curebase powered the behind-the-scenes eClinical platform. Patients received personalized email and SMS outreach inviting them to learn more about the study. The tone was clear and human, the ask was low-friction, and the path forward was simple: click, read, and answer a few questions.

The Experience

Interested patients were guided through a Curebase-hosted digital prescreening flow designed to feel smooth and easy-to-use. On any device, at any time, patients could work through eligibility questions at their own pace.

They were also able to select a site that would work best for them, rather than being automatically assigned one based on zipcode. For a cardiovascular population that skews older and may have limited bandwidth for complicated processes, this was really important.

The Results

Within the first 30 days of launch, the campaign had referred over 450 patients into the study pipeline.

28% of people who completed pre-screening were 70+ years old. The oldest participant that completed pre-screening was 92. Curebase's eClinical platform powered the process, including campaigns, ePRO for clinical trials, and eConsent. The sponsor did not need to build new infrastructure or retrain staff, they just needed a platform that already knew how to do this. And the Curebase eClinical platform was there to solve the challenge!